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Disseminated intravascular coagulation secondary to postpartum hemorrhage complicated with autoimmune hemolytic

Chunlei Ma1, Qian Liang1, Shurong Song1

  • 1Department of Obstetrics, The Third Central Hospital of Tianjin, China.

The Journal of International Medical Research
|January 23, 2026
PubMed

This study reported a case of disseminated intravascular coagulation secondary to postpartum hemorrhage complicated by autoimmune hemolytic anemia. A pregnant woman in her early 40s was admitted to The Third Central Hospital of Tianjin with regular contractions in July 2022. The direct antiglobulin test was positive for IgG and C3d. Following the delivery of a baby girl, she developed severe postpartum hemorrhage, and the obstetric disseminated intravascular coagulation score exceeded 8 points. She was diagnosed with disseminated intravascular coagulation secondary to postpartum hemorrhage and warm-antibody type autoimmune hemolytic anemia (IgG + C3). The patient underwent methylprednisone therapy, emergency selective bilateral uterine artery embolization, and transfusion with suspended and washed red blood cells. Subsequently, routine coagulation parameters normalized, and the urine color gradually cleared. Therefore, glucocorticoids, uterine artery embolization, and blood transfusion may be effective for managing disseminated intravascular coagulation secondary to postpartum hemorrhage complicated by autoimmune hemolytic anemia.

Keywords:
Autoimmune hemolytic anemiacase reportdisseminated intravascular coagulationpostpartum hemorrhagepregnancy

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