Related Experiment Video

Updated: Jan 25, 2026

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

732

Impact of low body mass index on stroke outcomes: A propensity-matched analysis

Barbara Buccilli1

  • 1Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|January 23, 2026
PubMed

Insights

Underweight patients (BMI < 19.9) face worse outcomes after ischemic stroke, including poor functional recovery and increased pneumonia risk. Nutritional status is crucial for stroke care planning and risk stratification.

Area of Science:

  • Neurology
  • Clinical Nutrition
  • Public Health

Background:

  • Body mass index (BMI) significantly impacts stroke outcomes.
  • The specific effects of being underweight (BMI < 19.9) on post-stroke prognosis are not well-understood.
  • This study investigates the association between underweight status and adverse outcomes following ischemic stroke.

Purpose of the Study:

  • To evaluate functional and clinical outcomes in ischemic stroke patients with underweight BMI compared to those with ideal BMI (20-24.9).
  • To determine if low BMI is a risk factor for poorer recovery and increased complications post-stroke.

Main Methods:

  • Utilized TriNetX data from the Mount Sinai Health System for adult ischemic stroke patients.
  • Cohorts were categorized by BMI: ideal weight (20-24.9) and underweight (<19.9).
  • Propensity score matching balanced 1,600 patients per group for a 2-year outcome assessment including modified Rankin Scale (mRS), pneumonia, and survival.

Main Results:

  • Underweight patients exhibited a higher incidence of poor functional outcome (mRS > 2: 18.1% vs 14.4%) and lower 2-year survival probability (79.3% vs 83.7%).
  • Pneumonia occurred more frequently in the underweight group (8.8% vs 6.9%).
  • No significant differences were found in repeat stroke, motor deficits, hemorrhagic transformation, or need for advanced interventions like thrombolytics or thrombectomy.

Conclusions:

  • Underweight status is significantly associated with poorer functional outcomes, increased risk of pneumonia, and reduced survival after ischemic stroke.
  • Nutritional status should be considered in the planning of post-stroke care.
  • Identifying underweight patients can aid in stroke risk stratification and management.
Abstract

Keywords:
BMIBody mass indexStrokeUnderweight

More Related Videos

High Throughput Analysis of Liquid Droplet Impacts09:00

High Throughput Analysis of Liquid Droplet Impacts

Published on: March 6, 2020

7.0K
Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry05:48

Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry

Published on: September 5, 2014

10.0K

Related Concept Videos

Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
509
Reduced Mass Coordinates: Isolated Two-body Problem01:12

Reduced Mass Coordinates: Isolated Two-body Problem

In classical mechanics, the two-body problem is one of the fundamental problems describing the motion of two interacting bodies under gravity or any other central force. When considering the motion of two bodies, one of the most important concepts is the reduced mass coordinates, a quantity that allows the two-body problem to be solved like a single-body problem. In these circumstances, it is assumed that a single body with reduced mass revolves around another body fixed in a position with an...
2.4K
Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
392
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.4K
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
1.7K
Impact of Groups on Groups01:19

Impact of Groups on Groups

Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
237