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Updated: Jan 25, 2026
13:15
Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
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Smart and wearable electrochemical biosensors in biomedical diagnostics
Palanisamy Kannan1, Govindhan Maduraiveeran2
1College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314 001, People's Republic of China.
Advances in Colloid and Interface Science
|January 23, 2026
Summary
Smart wearable biosensors use nanomaterials for real-time health monitoring. These advanced electrochemical devices offer sensitive and selective detection of biomarkers in biofluids for improved diagnostics.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Electrochemistry
Background:
- Smart and wearable biomolecular diagnostics are revolutionizing continuous biomarker monitoring in biofluids.
- Miniaturized electrochemical biosensors, particularly for point-of-care (POC) applications, are advancing rapidly due to nanomaterial innovations.
- Nanomaterials enhance biosensor sensitivity and selectivity through enzyme-mimetic catalysts and bio-affinity pairs.
Purpose of the Study:
- To review recent advancements in smart and wearable microbiosensors for point-of-care diagnostics.
- To highlight the role of nanomaterials in enhancing biosensor performance for diverse biofluid analysis.
- To discuss challenges and future perspectives in nanomaterial-enabled biosensing.
Main Methods:
- Review of recent literature on nanomaterial-based wearable biosensors.
- Emphasis on sensitivity, selectivity, reliability, and real-time performance metrics.
- Analysis of challenges such as stability, biocompatibility, and manufacturing.
Main Results:
- Functional nanomaterials integrated into wearable platforms enable high sensitivity, selectivity, and fast response times.
- Wearable biosensors facilitate reliable correlations between biomarker concentrations in various biofluids.
- Nanomaterials are crucial as interfacial and sensing components in advanced biosensing systems.
Conclusions:
- Smart wearable microbiosensors show significant promise for personalized medicine and preventive healthcare.
- Continued research in nanomaterial-enabled biosensing is expected to drive progress in clinical decision-making.
- Addressing challenges in stability and manufacturing is key for widespread adoption of these diagnostic tools.
Keywords:
Biomedical diagnosticsClinical diagnosticsElectroanalysisMicrobiosensorsNanomaterialsSmart sensorWearable sensorMore Related Videos
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