Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atherosclerosis III: Management01:26

Atherosclerosis III: Management

350
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
350
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

996
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
996
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

495
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
495
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

404
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
404
Reaction Mechanisms03:06

Reaction Mechanisms

30.6K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
30.6K
Mechanical Protein Functions01:58

Mechanical Protein Functions

5.5K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality of care for migrant populations with type 2 diabetes mellitus in Italy: a retrospective analysis of data from the the Italian AMD (Associations of Medical Diabetologists) annals initiative.

Acta diabetologica·2026
Same author

Association between electronic cigarette use and prediabetes, diabetes, and insulin resistance: a systematic review and meta-analysis.

Internal and emergency medicine·2026
Same author

Causes and consequences of discontinuation of GLP1RAs or tirzepatide.

Nature reviews. Endocrinology·2026
Same author

A comparison of the effects of tirzepatide and dulaglutide on major kidney events in people with type 2 diabetes: pre-specified exploratory analyses of the SURPASS-CVOT trial.

The lancet. Diabetes & endocrinology·2026
Same author

CVOT Summit Report 2025: advances along the cardiovascular-kidney-metabolic disease continuum.

Cardiovascular diabetology·2026
Same author

Environmental Pollutant-Induced Cardiopathogenesis Through Immune Dysfunction: The Emerging Role of Micro- and Nanoplastics.

The Canadian journal of cardiology·2026
Same journal

Navigating the Computational Landscape for Drug Repurposing.

Annual review of pharmacology and toxicology·2026
Same journal

Treating Pregnant and Lactating Women: Insights from Clinical Pharmacology.

Annual review of pharmacology and toxicology·2026
Same journal

<i>Caenorhabditis elegans</i> as a Model System for Environmental Mitotoxicants.

Annual review of pharmacology and toxicology·2025
Same journal

Introduction to the Theme "New Approaches, Technology, and Techniques That Advance Pharmacology and Toxicology".

Annual review of pharmacology and toxicology·2025
Same journal

A Mechanistic Framework for Repurposing FDA-Approved Drugs to Combat Antimicrobial Resistance: The Case of <i>Staphylococcus aureus</i>.

Annual review of pharmacology and toxicology·2025
Same journal

Early Detection of Wellness-to-Disease Transitions in the AI Era: Implications for Pharmacology and Toxicology.

Annual review of pharmacology and toxicology·2025
See all related articles

Related Experiment Video

Updated: Jan 25, 2026

Sampling and Identification of Microplastics in Groundwater
08:27

Sampling and Identification of Microplastics in Groundwater

Published on: November 7, 2025

1.1K

Microplastics and Atherosclerosis: Mechanisms.

Raffaele Marfella1,2, Francesco Prattichizzo3, Michelangela Barbieri1,2

  • 1Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy;

Annual Review of Pharmacology and Toxicology
|January 23, 2026
PubMed
Summary
This summary is machine-generated.

Microplastics and nanoplastics (MNPs) may impact cardiovascular health by disrupting biological processes. Further research using advanced detection techniques is needed to clarify the link between MNPs and cardiovascular diseases.

Keywords:
cardiovascular diseaseinflammationmass-based approachesmicro- and nanoplasticsomics approachoxidative stressparticle-based methods

More Related Videos

Separation and Identification of Conventional Microplastics from Farmland Soils
14:10

Separation and Identification of Conventional Microplastics from Farmland Soils

Published on: March 21, 2025

3.2K
Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis
10:16

Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis

Published on: December 16, 2016

50.8K

Related Experiment Videos

Last Updated: Jan 25, 2026

Sampling and Identification of Microplastics in Groundwater
08:27

Sampling and Identification of Microplastics in Groundwater

Published on: November 7, 2025

1.1K
Separation and Identification of Conventional Microplastics from Farmland Soils
14:10

Separation and Identification of Conventional Microplastics from Farmland Soils

Published on: March 21, 2025

3.2K
Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis
10:16

Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis

Published on: December 16, 2016

50.8K

Area of Science:

  • Environmental Health
  • Toxicology
  • Cardiovascular Science

Background:

  • Microplastics and nanoplastics (MNPs) are environmental pollutants with potential health implications.
  • Exposure can occur through ingestion, inhalation, or skin contact, leading to disruptions in cellular processes.
  • MNPs are suspected to contribute to cardiovascular diseases, but the direct link is not yet fully established.

Purpose of the Study:

  • To review current techniques for detecting and characterizing MNPs in human tissues.
  • To summarize the known mechanisms by which MNPs affect human health, with a focus on the cardiovascular system.
  • To highlight the need for further research to understand the impact of MNPs on cardiovascular health.

Main Methods:

  • Literature review of existing analytical techniques for MNP detection and characterization.
  • Synthesis of current scientific understanding of MNP interactions with biological systems.
  • Focus on studies investigating MNP effects on cardiovascular health.

Main Results:

  • MNPs can disrupt key biological pathways including autophagy, inflammation, oxidative stress, immune response, and vascular function.
  • Current data is inconsistent regarding the correlation between MNP concentration in tissues and cardiovascular disease onset.
  • Advancements in analytical techniques are crucial for future research.

Conclusions:

  • MNPs pose a potential risk to cardiovascular health through various biological disruption mechanisms.
  • More robust analytical methods are required to accurately quantify MNP presence and understand their dose-dependent effects.
  • Further prospective studies are necessary to establish a definitive link between MNP exposure and cardiovascular disease development.