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Updated: Jan 25, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease
Blake Hale1,2, Anna Latorre3, Lorenzo Rocchi4
1Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK. blake.hale@nhs.net.
None:
Optimal subthalamic nucleus deep-brain stimulation (STN-DBS) for Parkinson's disease reduces motor symptoms without stimulating adjacent structures and causing side-effects. Fine-tuning STN-DBS using clinical evaluation is time-consuming and often requires multiple follow-ups. Electrophysiological recordings may enhance STN-DBS device programming for clinicians by providing objective evidence of neural pathway activation. This literature review critically evaluates evoked potentials as biomarkers of optimal STN-DBS and assesses potential integration into the device programming toolkit.
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