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Photobiomodulation Increases Eye Movement Conjugation in Healthy Volunteers
Alex O Trofimov1,2, Elizabeth Kalinkina1, Alexander Lazarev1
1Department of Neurological Diseases, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Advances in Experimental Medicine and Biology
|January 23, 2026
Summary
Transcranial photobiomodulation (tPBM) significantly enhances eye movement conjugation in healthy individuals. This non-invasive therapy improves vergence reactivity indices, suggesting better eye coordination after treatment.
Area of Science:
- Neuroscience
- Ophthalmology
- Biomedical Engineering
Background:
- Eye movement conjugation is crucial for binocular vision.
- Photobiomodulation is an emerging therapeutic modality.
- Understanding tPBM's effects on oculomotor function is important.
Purpose of the Study:
- To evaluate changes in eye movement conjugation after transcranial photobiomodulation (tPBM).
- To assess the impact of tPBM on vergence reactivity index (VRx).
Main Methods:
- 54 healthy volunteers underwent eye tracking (20 Hz) before and after 10-minute tPBM (810 nm).
- Angular velocities (vertical and horizontal) were calculated to determine the vergence reactivity index (VRx).
- Statistical analysis included Pearson's correlation coefficients and the Wilcoxon T-criterion (p < 0.05).
Main Results:
- Vertical VRx increased significantly from 0.783 [0.702; 0.829] to 0.878 [0.843; 0.902] (p < 0.001).
- Horizontal VRx increased significantly from 0.927 [0.921; 0.93] to 0.875 [0.834; 0.912] (p < 0.001).
Conclusions:
- Transcranial PBM significantly improves eye movement conjugation.
- The study indicates enhanced vergence indices following tPBM treatment.
- tPBM shows potential for improving oculomotor control.
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