Related Experiment Video
Updated: Jan 25, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Skin-Reducing Mastectomy and Implant Reconstruction: Long-Term Surgical, Oncological, and Patient-Reported Outcomes
Gaik Si Quah1,2, Meagan Brennan1,2, James French1,2
1Westmead Breast Cancer Institute, Westmead Hospital, Westmead, New South Wales, Australia.
Skin-reducing mastectomy (SRM) offers immediate breast reconstruction for women with large breasts. Despite high complication rates, patient satisfaction remains high, with many willing to undergo the procedure again.
Area of Science:
- Plastic Surgery
- Breast Reconstruction
- Oncology
Background:
- Skin-reducing mastectomy (SRM) is a technique for immediate breast reconstruction using implants in women with large, ptotic breasts.
- Evaluating surgical and patient-reported outcomes (PRO) is crucial for understanding SRM's effectiveness.
Purpose of the Study:
- To assess the surgical outcomes of skin-reducing mastectomy (SRM).
- To evaluate patient-reported outcomes (PRO) following SRM using the BREAST-Q questionnaire.
- To analyze oncological outcomes and complication rates associated with SRM.
Main Methods:
- Retrospective analysis of patients undergoing SRM between January 2011 and December 2014.
- Collection of data on surgical complications, oncological outcomes, and PRO via BREAST-Q.
- Median follow-up of 10 years for long-term outcome assessment.
Main Results:
- 82.3% of 55 patients underwent SRM for cancer treatment; 83.6% had direct-to-implant reconstruction.
- Overall complication rate was 58.9%, with skin loss (24.2%) and capsular contracture (18.9%) being most common.
- At 10 years, local recurrence was 4.4%, overall survival 97.7%, disease-free survival 88.9%, with high patient satisfaction (76.5% would repeat SRM).
Conclusions:
- SRM facilitates immediate implant-based breast reconstruction in select patients with large breasts, potentially avoiding mesh use.
- While complication rates are notable, patient satisfaction with reconstructed breasts is high.
- SRM demonstrates favorable long-term oncological outcomes and high patient acceptance despite surgical challenges.
Related Concept Videos
Data Reporting and Recording
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Long-term Depression
Reducing Line Loss
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...

