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Tumor-Bearing Kidneys as Potential Donors: A National Survey From the United Kingdom

Farhad Janahi1, Muhammad Zeeshan Aslam, Matthew Trail

  • 1From the Department of Surgery, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai; and the Mediclinic City Hospital, Dubai, United Arab Emirates.

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation
|January 24, 2026
PubMed
Abstract

Insights

Clinicians in the UK support using tumor-bearing kidneys for transplantation to address organ shortages. This consensus suggests further trials are warranted to expand the donor pool for end-stage renal disease patients.

Area of Science:

  • Nephrology and Urology
  • Transplant Surgery

Background:

  • Kidney transplantation is crucial for end-stage renal disease, but organ scarcity is a global issue.
  • Utilizing kidneys with small, low-grade renal tumors (tumor-bearing kidneys) is a proposed strategy to increase donor organ availability.
  • Ex vivo resection of small renal tumors from donor kidneys is a key consideration.

Purpose of the Study:

  • To evaluate the perspectives of UK clinicians on using tumor-bearing kidneys for transplantation.
  • To gauge support among urologists, nephrologists, and transplant surgeons for this organ donation strategy.

Main Methods:

  • A national online survey was distributed to UK-based urologists, nephrologists, and transplant surgeons.
  • The survey was conducted between November and December 2019.
  • Response rate was 47% (108 out of 230 clinicians).

Main Results:

  • A significant proportion of clinicians expressed support for using tumor-bearing kidneys.
  • Support was highest among transplant surgeons (100%), followed by urologists (71%) and nephrologists (54%).

Conclusions:

  • Broad support exists among UK clinicians for the selective use of tumor-bearing kidneys in transplantation.
  • Despite ethical and logistical challenges, this consensus supports initiating formal trials.
  • Development of centralized protocols is recommended to enhance organ availability for kidney transplants.

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