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Correlation of Echocardiographic Parameters Including Myocardial Work Indices With Invasive Stroke Work Index in
Berhan Keskin1, Aykun Hakgor1, Oguz Karaca1
1Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Turkey.
Journal of Clinical Ultrasound : JCU
|January 24, 2026
Summary
Myocardial work indices, including LV-GCW and LV-GWI, more accurately estimate ventricular systolic function than standard measures in advanced heart failure patients undergoing heart transplant evaluation.
Area of Science:
- Cardiology
- Echocardiography
- Heart Failure Research
Background:
- Advanced heart failure necessitates accurate assessment of ventricular systolic function.
- Evaluating patients for heart transplantation requires precise functional metrics.
- Traditional echocardiographic parameters may not fully capture complex ventricular mechanics.
Purpose of the Study:
- To correlate echocardiographic myocardial work indices with invasive stroke work index (SWI) in advanced heart failure.
- To compare the accuracy of myocardial work indices versus standard echocardiographic measures in assessing left and right ventricular systolic function.
- To identify optimal echocardiographic parameters for evaluating heart transplant candidates.
Main Methods:
- Twenty-seven advanced heart failure patients underwent echocardiography and cardiac catheterization.
- Left ventricular (LV) and right ventricular (RV) systolic function parameters, including myocardial work indices, were measured.
- Spearman's correlation coefficient assessed relationships between echocardiographic measures and invasive SWI.
Main Results:
- LV global constructive work (LV-GCW) and LV global work index (LV-GWI) showed the strongest correlations with LV-SWI.
- LV ejection fraction (LVEF) and LV global longitudinal strain (LV-GLS) also correlated significantly with LV-SWI.
- RV global work index (RV-GWI) and tricuspid annular plane systolic excursion (TAPSE) showed moderate correlations with RV-SWI.
Conclusions:
- Myocardial work indices offer a more accurate estimation of ventricular systolic function in advanced heart failure compared to standard echocardiographic measures.
- These findings highlight the utility of myocardial work indices in assessing heart transplant candidates.
- Echocardiographic assessment of myocardial work provides valuable insights into ventricular performance.
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