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Published on: June 30, 2020
Long-term astigmatism progression and its interaction with spherical equivalent in Chinese school-age children: A
Zhuoer Qin1, Qiaolan Zheng1, Yuanyuan Liu1
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Insights
Astigmatism progression in Chinese children depends on initial severity. Higher myopia accelerated astigmatism, while higher astigmatism slightly protected against myopia progression.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Refractive Error Research
Background:
- Astigmatism and spherical equivalent (SE) changes are common in school-age children.
- Understanding the interplay between astigmatism and SE progression is crucial for myopia management.
- Longitudinal data on these refractive interactions in diverse populations are limited.
Purpose of the Study:
- To analyze longitudinal changes in astigmatism and its relationship with spherical equivalent (SE) progression.
- To investigate how baseline astigmatism severity influences its progression.
- To examine the interaction between astigmatism and SE changes in Chinese school-age children.
Main Methods:
- Retrospective analysis of medical records from 2946 Chinese children (aged 6-10 at baseline).
- Follow-up data collected between 2008 and 2022, with a minimum age of 16 at the last assessment.
- Astigmatism analyzed using clinical and vector notation (J0, J45); factors influencing annual changes in astigmatism and SE were assessed.
Main Results:
- Astigmatism cylinder power increased in low astigmatism (≤1.50 D) but decreased in high astigmatism (≥3.00 D).
- Oblique astigmatism (J45) increased, while with-the-rule astigmatism (J0) decreased over time.
- More negative baseline SE correlated with greater astigmatism increase; higher baseline astigmatism correlated with less SE progression.
Conclusions:
- Astigmatism progression in children is dependent on initial refractive error.
- Myopia is linked to accelerated astigmatism progression.
- Higher astigmatism offers a slight protective effect against myopic shift, though clinical significance is limited by small effect sizes.
Purpose:
To characterize longitudinal astigmatism changes and their interaction with spherical equivalent (SE) progression in Chinese school-age children.
Methods:
We retrospectively reviewed medical records of patients with long-term follow-up data from 2008 to 2022. Patients aged 6-10 years at initial visit and 16 years at last assessment, with a cylinder refraction of 0.75 D or greater, were selected. Astigmatism was analyzed in clinical notation and vector notation (J0, J45). Factors related to annual changes in astigmatism and SE and their interaction were analyzed.
Results:
A total of 2946 patients (mean age 8.72 ± 1.21 years at initial visit) were followed up for 7.40 ± 1.23 years. In low astigmatism (≤1.50 D), cylinder power increased by 0.018 D/y with age, whereas in high astigmatism (≥3.00 D), it decreased by 0.048 D/y (p < 0.001). Oblique astigmatism (J45) increased by 0.008 D/y, and with-the-rule (WTR) astigmatism (J0) decreased by 0.005 D/y (p < 0.001). A more negative baseline SE at initial visit was associated with greater increase in astigmatism magnitude (β = -0.004, p < 0.001), and higher baseline astigmatism magnitude was associated with less SE progression (β = 0.047, p < 0.001).
Conclusion:
In this large longitudinal cohort of Chinese school-age children, astigmatism progression exhibited a baseline-dependent pattern. Myopia was associated with a modest acceleration of astigmatism progression, whereas higher astigmatism conferred a slight protective effect against myopic shift. This study demonstrates these refractive interactions, though their clinical applicability is limited by small effect sizes.
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