Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions

Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions

Unless individual gases chemically react with each other, the individual gases in a mixture of gases do not affect each other’s pressure. Each gas in a mixture exerts the same pressure that it would exert if it were present alone in the container. The pressure exerted by each individual gas in a mixture is called its partial pressure.

Dalton's Law of Partial Pressure

Dalton's Law of Partial Pressure

The partial pressure of a gas is a measure of the thermodynamic activity of the gas's molecules. The pressure that a gas would create if it occupied the total volume available is called the gas's partial pressure. If two or more gases are mixed together in a container, the molecules move randomly and collide with each other, causing them to reach thermal equilibrium. When the gases have the same temperature, their molecules have the same average kinetic energy. Thus, each gas obeys the...

Dosage Regimens: Partial Pharmacokinetic Parameters

Dosage Regimens: Partial Pharmacokinetic Parameters

It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...

Inverse z-Transform by Partial Fraction Expansion

Inverse z-Transform by Partial Fraction Expansion

The inverse z-transform is a crucial technique for converting a function from its z-domain representation back to the time domain. One effective method for finding the inverse z-transform is the Partial Fraction Method, which involves decomposing a function into simpler fractions with distinct coefficients. These fractions correspond to known z-transform pairs, facilitating the inverse transformation process.
To begin the process, the poles of the function are identified and the function is...

Weak Base Solutions

Weak Base Solutions

Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...

Patient-centered Care

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Factors affecting color vision: a systematic review.

International journal of ophthalmology·2026

Same author

Evaluating corneal topographic patterns in keratoconic eyes and their association with keratoconus changes over time.

International journal of ophthalmology·2026

Same author

Predicting Keratoconus Progression From a Single Visit: Is Machine Learning Successful?

Eye & contact lens·2026

Same author

Deep-stromal implantation of a double-crosslinked bioengineered porcine collagen implant (BPCDX) in advanced keratoconus: a 12-month study of corneal remodeling and visual outcomes.

Scientific reports·2026

Same author

Comparative study of refractive errors between patients with Parkinson's disease versus age- and sex-matched healthy controls.

BMC neurology·2026

Same author

Comparison of binocular vision indices in Parkinson's disease patients <i>vs</i> age-sex-matched healthy controls.

International journal of ophthalmology·2026

Same journal

Serum vitamin D level and its association with vertigo frequency and severity in Meniere disease.

Scientific reports·2026

Same journal

PFA-Net: a physics-informed feature enhancement and attention network for interpretable bearing fault diagnosis under strong noise.

Scientific reports·2026

Same journal

Circulating inflammatory, redox, and apoptosis-related alterations in drug-naive idiopathic pulmonary fibrosis: an exploratory case-control study.

Scientific reports·2026

Same journal

A baseline-oriented dynamic aggregation approach for demand-side heterogeneous controllable resources.

Scientific reports·2026

Same journal

Temporal precision and accuracy in schizophrenia: an exploratory study.

Scientific reports·2026

Same journal

Prefrontal EEG spectral and nonlinear signatures of subthreshold depression during resting state and affectively valenced picture/video viewing: a participant-level analysis.

Scientific reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 26, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Agreement between Scheimpflug-based optical biometer with partial coherence interferometry in patients with

Hassan Hashemi¹, Alireza Jamali², Morad Amir Ahmad³

¹Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.

Scientific Reports

|January 24, 2026

Summary

This summary is machine-generated.

The Pentacam AXL and IOL Master 500 show good agreement for axial length in keratoconus patients. However, differences in keratometry and other measurements lead to variations in intraocular lens (IOL) power calculations.

Keywords:

Agreement Biometry IOL master 500 Keratoconus Pentacam AXL

More Related Videos

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Related Experiment Videos

Last Updated: Jan 26, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Area of Science:

Ophthalmology
Biomedical Engineering

Background:

Accurate intraocular lens (IOL) power calculation is crucial for successful refractive outcomes after cataract surgery.
Keratoconus (KCN) presents unique challenges for biometry due to corneal irregularity.
Comparing optical biometry devices is essential for clinical decision-making.

Purpose of the Study:

To assess the agreement between the Pentacam AXL and IOL Master 500 for measuring biometric parameters in keratoconus patients.
To evaluate the impact of device differences on intraocular lens (IOL) power calculations using various formulas.

Main Methods:

A cross-sectional study involving 121 eyes of patients over 60 with keratoconus and cataracts.
Optical biometry performed using both Pentacam AXL and IOL Master 500.
IOL power calculated using six formulas (Kane keratoconus, Barret universal 2, Holladay 1, Haigis, Hoffer Q, SRK/T) based on device measurements.
Agreement analyzed using the Bland-Altman method.

Main Results:

Good agreement was found for axial length measurements between the two devices (95% limits of agreement: -0.08 to 0.02).
Discrepancies were observed in keratometry (K1, K2), anterior chamber depth (ACD), and white-to-white (WTW) measurements.
Significant differences in IOL power calculations were noted, with the Pentacam AXL generally yielding higher power values.
The Hoffer Q formula showed the most pronounced difference (+0.55 ± 0.92), while Holladay 1 showed the least (+0.34 ± 1.98).

Conclusions:

The Pentacam AXL and IOL Master 500 demonstrate good agreement for axial length in keratoconus patients.
Differences in keratometry, ACD, and WTW measurements between devices impact IOL power calculations.
The choice of IOL calculation formula significantly influences the final power, with the Pentacam AXL and Kane keratoconus formula resulting in higher estimates.