Related Experiment Video
Updated: Jan 26, 2026
08:53
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
1.6K
Noninvasive BCI-based cognitive rehabilitation in poststroke cognitive impairment: study protocol for a randomized
Xinyue Niu1, Min Yuan2, Jie Zhang3
1School of Preclinical Medicine and School of Nursing, Chengdu University, Chengdu, China.
Trials
|January 24, 2026
Summary
This study investigates noninvasive brain-computer interface (BCI) cognitive training for poststroke cognitive impairment (PSCI). BCI neurofeedback may improve cognitive function and neural plasticity in stroke survivors.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Biomedical Engineering
Background:
- Poststroke cognitive impairment (PSCI) significantly impacts quality of life and survival.
- Current interventions for PSCI have limitations in efficacy and accessibility.
- Noninvasive brain-computer interface (BCI) technology offers a potential avenue for enhancing neural plasticity and cognitive recovery.
Purpose of the Study:
- To evaluate the efficacy of BCI-based cognitive training for PSCI.
- To explore the underlying neural mechanisms of cognitive recovery facilitated by BCI.
- To establish BCI as a safe and accessible tool for poststroke cognitive rehabilitation.
Main Methods:
- Prospective, randomized, double-blind, controlled trial with 66 PSCI patients.
- Intervention group receives BCI cognitive training 5 days/week for 4 weeks.
- Assessments include MoCA scores, cognitive functions, neurophysiological markers, and daily living function at baseline, post-intervention, and 3-month follow-up.
Main Results:
- Primary outcome: change in MoCA scores at 4 weeks post-intervention.
- Secondary outcomes: sustained cognitive improvements at 3-month follow-up.
- Exploration of neurophysiological markers to elucidate BCI's impact on neural plasticity.
Conclusions:
- Results are expected to demonstrate the clinical utility of BCI in PSCI.
- Evidence will be provided for BCI's role in modulating neuroplasticity mechanisms.
- Findings will inform personalized neurorehabilitation strategies for stroke survivors.
Keywords:
Brain-computer interfaceCognitive impairmentNeuroplasticityRandomized controlled trialStrokeMore Related Videos
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