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Published on: October 14, 2016
Understanding chronic myelomonocytic leukemia to improve nursing care
Emily Klepitsch1, Elena Ignatiev, Dorothy Georges
1Emily Klepitsch is an Oncology Staff Nurse at Northwestern Medicine, Central DuPage Hospital in Winfield, IL. Elena Ignatiev is a Clinical Assistant Professor at the University of Illinois at Chicago College of Nursing, and an Advanced Practice Provider at University of Chicago Department of Medicine Section of Gastrointestinal Oncology. Dorothy Georges is a Clinical Practice Specialist at Northwestern Medicine, Central DuPage Hospital. Karen Vuckovic is a Clinical Associate Professor in the College of Nursing at the University of Illinois at Chicago.
Abstract:
Chronic myelomonocytic leukemia (CMML) is a rare, aggressive type of leukemia that can exhibit myeloproliferative and myelodysplastic features and has a propensity to transform into acute myeloid leukemia (AML). CMML is characterized by specific cytogenetic abnormalities and identified laboratory findings that support the diagnosis. Clinical manifestations of the disorder depend on disease subtype. Current treatments are supportive with a goal of increasing time to transformation into AML and decreasing end-organ damage. The only known cure for CMML is allogeneic stem cell transplant. This article discusses the pathophysiology, diagnosis, complications, and management of CMML, as well as nursing considerations when caring for patients with this hematologic malignancy. It aims to define unique characteristics of CMML to aid nurses in providing effective care to these patients.
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