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Published on: September 25, 2009
Flow Diversion for Intracranial Aneurysms in Large-Diameter Vessels: A Subanalysis From the SESSIA Study
Juan Vivanco-Suarez1, Aaron Rodriguez-Calienes1,2, Mudassir Farooqui1
1Department of Neurology Neurosurgery and Radiology University of Iowa Hospitals and Clinics Iowa City IA.
Large-diameter flow diverters are safe and effective for treating intracranial aneurysms in large-diameter vessels (LDVs). Outcomes were comparable to standard-diameter devices, showing feasibility for this patient group.
Area of Science:
- Neurosurgery
- Interventional Neurology
- Medical Devices
Background:
- Flow diverters are standard treatment for intracranial aneurysms.
- Limited device options exist for large-diameter vessels (LDVs).
- This study assesses the largest available flow diverter for LDVs.
Purpose of the Study:
- Evaluate the safety and efficacy of the largest diameter Surpass Streamline flow diverter.
- Assess its performance in treating intracranial aneurysms within LDVs.
- Compare outcomes between LDV and non-LDV groups.
Main Methods:
- Subanalysis of the SESSIA multicenter cohort study (2018-2021).
- Included patients treated with 5-mm Surpass Streamline.
- Groups: LDV (vessel diameter ≥5.3 mm) vs. non-LDV (N-LDV, <5.3 mm).
- Efficacy: complete occlusion; Safety: ischemic/hemorrhagic events, mortality.
Main Results:
- 30 patients (15 LDV, 15 N-LDV) included; similar baseline characteristics.
- Vessel diameters differed significantly at landing zones (P<0.001).
- Complete occlusion rates were similar (LDV 75% vs. N-LDV 84%, P=0.548).
- Ischemic/hemorrhagic events were comparable (1 per group, P=1.00).
Conclusions:
- Large-diameter flow diverters are feasible and safe for intracranial aneurysms in LDVs.
- This device shows promising results in a challenging patient subset.
- Further comparative studies are needed for optimal device selection.
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