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Updated: Jan 27, 2026

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Preserving Function, Enhancing Precision: The Rise of Personalized Endonasal Sinus Surgery.

Lino Di Rienzo Businco1, Abdillah Hasbi Assadyk2

  • 1Department of Otorhinolaryngology, UBRI (Ultrastructural Biophysics Research Institute) Institute and San Giovanni Battista Hospital, Order of Malta, Rome, ITA.

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|January 26, 2026
PubMed
Summary
This summary is machine-generated.

Thinvasive surgery offers a minimally invasive, function-preserving approach to managing chronic rhinosinusitis (CRS). This paradigm integrates modern endoscopic sinus surgery techniques with advanced patient assessment for personalized treatment.

Keywords:
balloon sinuplastychronic rhinosinusitisendoscopic sinus surgerykinetic oscillation stimulationmucosal preservationpersonalized surgeryquantum molecular resonancethinvasive

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Area of Science:

  • Otolaryngology
  • Surgical Innovation
  • Rhinosinusitis Management

Background:

  • Chronic rhinosinusitis (CRS) is a prevalent condition significantly affecting patient quality of life.
  • Management of CRS has evolved with surgical advancements and improved understanding of mucosal pathophysiology.
  • A gap exists in literature regarding the integration of novel techniques into CRS surgical management.

Purpose of the Study:

  • To review the evolution of endonasal sinus surgery.
  • To present the concept of "Thinvasive" surgery as a modern paradigm for CRS management.
  • To discuss the integration of current innovations and patient-specific assessment strategies.

Main Methods:

  • Comprehensive literature review of historical and current endoscopic sinus surgery techniques.
  • Analysis of advancements including image-guided FESS and balloon sinuplasty.
  • Evaluation of the Thinvasive approach incorporating radiologic and functional assessment tools.

Main Results:

  • The evolution from external procedures to functional endoscopic sinus surgery (FESS) emphasized mucosal preservation.
  • Minimal-access modalities like image-guided FESS and balloon sinuplasty enable precise interventions.
  • The Thinvasive approach combines these innovations with patient-specific assessments for personalized CRS care.

Conclusions:

  • Thinvasive surgery represents a promising hybrid between medical and surgical treatments for CRS.
  • This approach integrates current endoscopic sinus surgery advancements with tailored patient evaluation.
  • Further research is required to establish long-term efficacy and standardize patient selection for Thinvasive techniques.