Dedifferentiated Liposarcoma With Low-Grade Osteosarcomatous Differentiation: A Rare Case With Long-Term Imaging

Kanae Takahashi1, Takuya Adachi1, Yuki Funauchi2

  • 1Department of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, JPN.

Cureus
|January 26, 2026
PubMed
Summary

Dedifferentiated liposarcoma (DDLPS) with osteosarcomatous differentiation is rare but carries a high recurrence risk. Gradual calcification growth in lipomas may signal this aggressive DDLPS subtype, aiding early diagnosis.

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