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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

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In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
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EUS in pediatric patients.

Christoph F Dietrich1, Barbara Braden2, Kathleen Möller3

  • 1Department General Internal Medicine (DAIM), Hospitals Hirslanden Bern Beau Site, Salem and Permanence, Bern, Switzerland.

Endoscopic Ultrasound
|January 26, 2026
PubMed
Summary
This summary is machine-generated.

Endoscopic ultrasound (EUS) offers high-resolution, radiation-free imaging for pediatric gastrointestinal diseases. Increased training and availability are crucial to overcome underutilization and improve pediatric patient care.

Keywords:
DiagnosisEUSPediatricTreatment

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Area of Science:

  • Pediatric Gastroenterology
  • Medical Imaging
  • Diagnostic Endoscopy

Background:

  • Endoscopic ultrasound (EUS) is a valuable tool in pediatric gastroenterology.
  • It provides high-resolution imaging of the gastrointestinal tract and adjacent organs.
  • EUS is particularly useful for diagnosing abdominal diseases without radiation exposure.

Purpose of the Study:

  • To review the clinical applications and outcomes of EUS in pediatric patients.
  • To highlight the diagnostic and therapeutic potential of EUS in pediatric gastrointestinal, pancreatic, biliary, and intestinal diseases.
  • To address the underutilization of EUS in pediatric care.

Main Methods:

  • Literature review of clinical applications and outcomes of EUS in pediatric gastroenterology.
  • Analysis of EUS efficacy in diagnosing and managing various pediatric diseases.
  • Identification of challenges and barriers to EUS utilization in children.

Main Results:

  • EUS demonstrates accuracy and high-resolution imaging capabilities for pediatric abdominal conditions.
  • It offers a radiation-free alternative to other imaging modalities.
  • Despite proven efficacy, EUS is underutilized in pediatric settings due to technical challenges and lack of specialized expertise.

Conclusions:

  • EUS is an essential, effective imaging tool for pediatric gastroenterology.
  • Enhancing the availability and specialized training for pediatric EUS is critical.
  • Increased access to pediatric EUS will improve diagnostic precision and therapeutic outcomes for children.