Related Experiment Video
Updated: Jan 28, 2026

08:22
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
5.2K
Bilateral Peripheral Neovascularization in Hemoglobin C Trait Retinopathy
Jordan Jabara1, Benjamin West2, Viren K Govindaraju3
1Beaumont Eye Institute, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA.
Journal of Vitreoretinal Diseases
|January 26, 2026
Summary
Hemoglobin C trait can cause peripheral neovascularization (NV), a rare condition. Screening for hemoglobinopathies is crucial for diagnosing systemic diseases presenting with peripheral NV.
Area of Science:
- Ophthalmology
- Hematology
Background:
- Peripheral neovascularization (NV) is an abnormal growth of blood vessels.
- Hemoglobinopathies are a group of inherited blood disorders.
Related Concept Videos
Multiple Allele Traits
38.1K
The Concept of Multiple Allelism
38.1K
Trait and State Self-Esteem
11.5K
The term self-esteem is often used generically, to refer to how people feel about themselves. However, according to research, there are three distinct constructs that should not be used interchangeably (Brown & Marshall, 2006).
11.5K
Polygenic Traits
69.0K
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
69.0K
Hemoglobin
8.2K
Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
8.2K
Traits and States
546
Personality traits represent consistent patterns in behavior, thoughts, and emotions, reflecting an individual's tendencies across various situations. For example, extraversion, a well-known trait, manifests in individuals as talkative, energetic, and enthusiastic behaviors. These traits are stable over time, offering a reliable framework for predicting how people might act in different contexts. However, they do not define every moment of an individual's life. In contrast to traits,...
546
X-linked Traits
58.6K
In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be masked by the presence of a normal allele on the second X. In contrast, a mutation on the X chromosome in males more often causes observable biological defects, as there is no normal X to compensate. Trait variations arising from mutations on the X chromosome are called “X-linked”.
58.6K

