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Outcomes After Proximal Humerus Surgery: Does Regional Anesthesia Usage Matter?

Bill Young1, Amy L Ladd1

  • 1Department of Orthopaedic Surgery, Stanford University, Stanford, CA.

Journal of Hand Surgery Global Online
|January 26, 2026
PubMed
Summary
This summary is machine-generated.

Regional anesthesia for proximal humerus fracture surgery increased emergency department visits and opioid prescriptions. Further research is needed to reduce these adverse events in patients receiving regional anesthesia.

Keywords:
Emergency departmentlFractureOpioidProximal humerusRegional anesthesia

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Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Health Services Research

Background:

  • Regional anesthesia is a common method for managing pain during proximal humerus fracture surgery.
  • General anesthesia is an alternative approach for pain management in these procedures.

Purpose of the Study:

  • To investigate the association between regional anesthesia and postoperative outcomes in proximal humerus fracture surgery.
  • To compare emergency department (ED) utilization, perioperative opioid prescriptions, and persistent opioid use between regional and general anesthesia groups.

Main Methods:

  • Retrospective analysis of patients undergoing open reduction internal fixation (ORIF) or shoulder arthroplasty for proximal humerus fractures.
  • Propensity-score matching was used to compare patients who received regional anesthesia versus general anesthesia.
  • Outcomes included ED visits within 7 and 30 days, and perioperative and persistent opioid prescriptions.

Main Results:

  • Regional anesthesia was associated with a significant increase in ED visits within 7 and 30 days post-surgery for both ORIF and shoulder arthroplasty patients.
  • Patients receiving regional anesthesia also had greater perioperative opioid prescriptions compared to those receiving general anesthesia.
  • A higher incidence of persistent postoperative opioid prescriptions was observed in the regional anesthesia group, though not explicitly detailed in the provided text.

Conclusions:

  • Regional anesthesia for proximal humerus fracture surgery is linked to increased postoperative ED utilization and higher opioid prescription rates.
  • Interventions are needed to mitigate potential adverse events associated with regional anesthesia in this patient population.
  • Further investigation into reducing ED visits and opioid-related complications is warranted.