Related Experiment Video
Updated: Jan 28, 2026

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016
Quantification of Articular Surface Involvement During Intramedullary Fixation of the Phalanges
Julie Mekhail1, Rhiana Rivas1, Carolyn A Ardizzone1
1University of New Mexico School of Medicine, Albuquerque, NM.
Purpose:
Phalangeal fractures of the hand are the second most common upper-extremity fracture in the United States. Numerous studies have reported on the biomechanical efficacy of intramedullary (IM) hand nail fixation of the phalanges and increased utilization of IM hand nails. During IM fixation, the nail often penetrates the articular cartilage during insertion. This study seeks to quantify the percentage of cartilage involvement created by anterograde and retrograde intramedullary fixation of proximal and middle phalangeal fractures with 3.0 mm and 3.5 mm IM threaded hand nails.
Methods:
Thirty-two frozen fingers were studied from eight cadaveric hands. Four different techniques for nail placement were used: (1) retrograde across an unflexed distal interphalangeal joint, (2) retrograde across a flexed distal interphalangeal joint into the middle phalanx, (3) retrograde through a flexed proximal interphalangeal joint into the proximal phalanx, and 4) antegrade through the metacarpal phalangeal joint into the proximal phalanx. Clinical photographs and fluoroscopy images were taken for each specimen, and the articular cartilage damage was quantified using Image J software.
Results:
The average articular involvement using intramedullary hand nails for phalangeal fixation was less than 10% of the articular surface regardless of nail placement technique and nail size (mean range 3.56% to 9.73%). The damaged area was always greater with the 3.5 mm than the 3.0 mm nails.
Conclusions:
Our results are consistent with the literature. Our study is unique in that we compare the different methods of hand nail insertion and the different diameter hand nails and evaluate the degree of articular surface involvement in an approach that has not been tested on cadaveric models. Phalanx fracture fixation with intramedullary hand nails may be beneficial, as it has acceptable joint cartilage damage based on our study data.
Type Of Study/Level Of Evidence:
Bench research/laboratory study V.
Related Concept Videos
Fixation and Sectioning
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
Carbon-dioxide Fixation
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and...
Surface Tension and Surface Energy
Consider a beaker filled with liquid. The bulk molecules in the liquid experience equal attractive forces on all sides with the surrounding molecules. However, the surface molecules experience a net attractive force downward due to the bulk molecules. The surface of the liquid behaves like a stretched membrane,...
Wood Surfacing
The equipment used in the surfacing process is a plane equipped with rotating blades. This tool efficiently smoothens the wood surface and can...
Cell-surface Signaling

