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Published on: October 17, 2025
Ferroptosis: a new dawn in the treatment of acute lymphoblastic leukemia
Jiongping Han1, Yifan Yang1, Yuxin Wei1
1Department of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.
Abstract:
Acute lymphoblastic leukemia poses substantial challenges in therapeutic management. As a novel form of programmed cell death, ferroptosis has emerged as a promising research direction in cancer therapy. Studies have emphasized the pivotal role of ferroptosis in ALL, indicating that targeting this pathway could provide a novel therapeutic strategy. This article systematically reviews the molecular regulatory mechanisms of ferroptosis in ALL and explores its potential clinical applications in the treatment and prognostic evaluation of the disease.
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