Related Experiment Video
Updated: Jan 28, 2026
10:45
Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space
Published on: July 24, 2017
12.7K
Tenzing 7 Delivery Catheter Performance Across Tortuosity Indices
Manisha Koneru1, Clint A Badger1,2, Fabio Settecase3,4
1Cooper Medical School of Rowan University Camden NJ.
Stroke (Hoboken, N.J.)
|January 26, 2026
Summary
The Tenzing 7 (T7) catheter successfully delivered large aspiration catheters in 95.3% of acute ischemic stroke cases, regardless of internal carotid artery (ICA) tortuosity. This device is effective for endovascular thrombectomy in patients with complex vascular anatomy.
Area of Science:
- Neurology
- Interventional Neuroradiology
- Medical Devices
Background:
- The Tenzing 7 (T7) delivery catheter is designed to overcome challenges in navigating tortuous neurovasculature.
- Its flexible tip aims to reduce the 'ledge effect' during intracranial procedures.
- This study evaluates the T7 catheter's performance in internal carotid arteries (ICAs) with varying degrees of tortuosity.
Purpose of the Study:
- To characterize the performance of the Tenzing 7 (T7) delivery catheter in patients undergoing aspiration thrombectomy for acute ischemic stroke.
- To assess the impact of internal carotid artery (ICA) tortuosity on T7 catheter success rates and procedural outcomes.
Main Methods:
- Retrospective analysis of prospectively collected data from 107 patients treated between January 2020 and July 2022.
- Internal carotid artery (ICA) tortuosity index (TI) calculated from digital subtraction angiography.
- T7 success defined as delivery to the occlusion face; regression analysis used to assess TI correlation with success and outcomes.
Main Results:
- The T7 catheter achieved a technical success rate of 95.3% (102/107 patients).
- No significant association was found between ICA tortuosity index (TI) and T7 technical success (P = 0.23).
- Higher tortuosity did not correlate with worse intraprocedural outcomes.
Conclusions:
- The Tenzing 7 (T7) delivery catheter demonstrates high efficacy in intracranial delivery, even in highly tortuous extracranial vasculature.
- Procedural success and performance were consistent regardless of ICA tortuosity.
- The T7 catheter is a suitable option for aspiration endovascular thrombectomy in acute stroke patients with tortuous vasculature.
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