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Updated: Jan 27, 2026

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
Isolated knee septic arthritis revealing disseminated coccidioidomycosis without apparent pulmonary involvement: A
Elias Ledezma Flores1, Arturo Urias Pompa2, Ariadna Betsabel Heredia Pulido3
1Faculty of Medicine, Universidad Xochicalco, Rampa Yumalinda 4850, Chapultepec Alamar, 22110 Tijuana, Baja California, México.
Abstract:
Coccidioidomycosis is an endemic fungal infection that rarely presents as isolated osteoarticular disease in immunocompetent hosts. We report a case of disseminated coccidioidomycosis manifesting as chronic septic arthritis of the tibiofemoral joint without apparent pulmonary involvement in a 32-year-old male. Diagnostic delay and initial immunosuppressive therapy contributed to disease progression. Histopathology confirmed the diagnosis and combined surgical debridement and prolonged antifungal therapy led to favorable outcomes. This case highlights the importance of considering fungal etiologies in chronic monoarthritis in endemic regions.
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