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Monkeypox: Skin Lesion Spread From Initial Contact in Three Cases
Lusheng Miao1, Guofei Yang1, Jizhao Yao1
1From the Department of Dermatology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Abstract:
Monkeypox is a zoonosis caused by the monkeypox virus. In 2022, the World Health Organization declared monkeypox a Public Health Emergency of International Concern due to its unprecedented global spread. Since June 2023, several new cases have re-emerged in mainland China, underscoring the ongoing transmission risk. Our three cases, confirmed by real-time quantitative polymerase chain reaction with dermoscopic and histopathological findings supporting diagnosis, exhibited atypical symptoms consistent with skin contact-mediated transmission. We propose that, in some patients, lesions may initially develop at the site of contact without preceding systemic symptoms and later disseminate to other body regions.
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