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Updated: Jan 27, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Axillary artery thrombus in a patient with critical bicuspid aortic stenosis
Lucy Searle1, Emma Walsh1, Sirpi Malar Selvaraju2
1Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Abstract:
Severe aortic stenosis typically presents with reduced exercise tolerance, exertional chest pains, or syncope. We report on a case of a young female on therapeutic anticoagulation and a history of nephrotic syndrome, who presented with subacute limb ischaemia resulting from axillary artery thrombus. Urgent echocardiogram demonstrated a bicuspid aortic valve with critical stenosis, and she underwent surgical aortic valve replacement. Her presenting symptoms resolved after three months of warfarin therapy. This case highlights the importance of systemic evaluation of unexplained arterial thrombosis.
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