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The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
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Does endoscopic magnetic resonance imaging challenge EUS?

Peng Wu1, Wenxin Zhang2, Tingting Wang1

  • 1Department of Gastroenterology, Endoscopic Center, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.

Endoscopic Ultrasound
|January 26, 2026
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Summary

A new wireless endoscopic magnetic resonance imaging (EndoMRI) system with balloon stabilization improves diagnostic accuracy for digestive diseases by providing stable imaging, overcoming limitations of current endoscopic ultrasound (EUS).

Keywords:
Balloon stabilizationDigestive system imagingEUSEndoscopic magnetic resonance imagingEsophageal imagingImage quality assessmentInductive couplingWireless coil technology

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Area of Science:

  • Medical Imaging
  • Gastroenterology
  • Biomedical Engineering

Background:

  • Endoscopic ultrasound (EUS) is vital for digestive disease diagnosis but limited by motion and gas interference.
  • Physiological motion and gas artifacts compromise the diagnostic accuracy of conventional EUS.
  • A novel solution is needed to enhance imaging stability and reliability in endoscopic procedures.

Purpose of the Study:

  • To develop and evaluate a wireless endoscopic magnetic resonance imaging (EndoMRI) system.
  • To address limitations of EUS by incorporating balloon-assisted stabilization technology.
  • To assess the performance of EndoMRI for digestive system evaluation.

Main Methods:

  • A wireless EndoMRI system with a novel coil using inductive coupling was designed.
  • An inflatable balloon was integrated for optimal coil positioning within a 10-35 mm diameter range.
  • System performance was evaluated on ex vivo porcine esophagi at 5.0T, comparing with miniprobe EUS.

Main Results:

  • EndoMRI demonstrated significantly superior esophageal image stability compared to EUS microprobes (P < 0.05).
  • EndoMRI signal continuity strongly correlated with histopathological findings in a thermal injury model, enabling accurate lesion assessment.
  • The wireless balloon-equipped EndoMRI system provided stable, reliable, continuous imaging of ex vivo esophagi.

Conclusions:

  • Endoscopic magnetic resonance imaging (EndoMRI) offers enhanced stability and diagnostic capability.
  • The wireless, balloon-assisted system overcomes key limitations of current endoscopic imaging techniques.
  • EndoMRI shows promise as an advanced technology for evaluating digestive system diseases.