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Biological Matrix-Assisted Apexification: A Case Report Using PRF and MTA in Immature Necrotic Teeth.

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Treating infected immature teeth requires inducing an apical barrier. Platelet-rich fibrin (PRF) combined with mineral trioxide aggregate (MTA) shows promise for apexification, though disinfection may require multiple visits.

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Area of Science:

  • Dentistry
  • Regenerative Endodontics
  • Biomaterials

Background:

  • Treating infected nonvital immature permanent teeth presents challenges due to the absence of natural apical constriction.
  • Traditional apexification using calcium hydroxide involves lengthy treatment times and unpredictable outcomes.
  • Mineral trioxide aggregate (MTA) offers a faster, more predictable alternative for inducing an apical barrier.

Purpose of the Study:

  • To present a case report on using platelet-rich fibrin (PRF) as a biological matrix with MTA for apexification.
  • To evaluate the efficacy of this combined approach in immature necrotic teeth.

Main Methods:

  • A case report detailing the endodontic treatment of an immature necrotic tooth.
  • Utilized mineral trioxide aggregate (MTA) in conjunction with platelet-rich fibrin (PRF) for apexification.
  • A multi-visit approach was adopted due to persistent exudate, prioritizing thorough disinfection.

Main Results:

  • The combination of MTA and PRF was employed for apexification in an immature necrotic tooth.
  • Persistent exudate necessitated a staged treatment protocol for adequate disinfection.
  • The final obturation was performed after achieving a disinfected environment.

Conclusions:

  • Platelet-rich fibrin (PRF) can serve as a biological internal matrix in conjunction with MTA for apexification.
  • While a single visit was initially considered, achieving adequate disinfection is paramount, potentially requiring multiple visits.
  • This approach offers a promising alternative for managing immature necrotic teeth.