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Updated: Jan 28, 2026

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Sublingual Nitroglycerin Administration to Relieve Radial Artery Vasospasm and Retrieve Wedged Catheter: A
Asad S Akhter1, Richard Gumina2, Shahid Nimjee3
1The Ohio State University Wexner Medical Center Columbus OH.
Background:
Radial artery spasm is a common hinderance during transradial approaches for neuroangiography. Ways of alleviation have been described, including patient sedation, local lidocaine, or even prophylactic administration of intra-arterial vasodilators.
Methods:
We present a case of a wedged catheter attributable to radial artery spasm, which failed all conventional methods to relieve spasm.
Results:
The catheter was ultimately removed after administration of sublingual nitroglycerin.
Conclusion:
To our knowledge, this is the first time sublingual nitrogen has been reported as an effective means to alleviate radial artery spasm during a transradial approach for neuroangiography.
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