Related Experiment Video
Updated: Jan 28, 2026
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Role of Computed Tomography Angiography Enhancement Ratio in Predicting Prognosis in Patients With Stroke Undergoing
Anyu Liao1, Lijun Huang2, Kangmo Huang1
1Department of Neurology Nanjing Jinling Hospital Affiliated Hospital of Medical School Nanjing University Nanjing China.
Background:
The computed tomography angiography enhancement ratio (CTA-ER), calculated through the net water uptake formula, is a valuable predictive tool for detecting adverse events after stroke. However, limited research has investigated the correlation between CTA-ER and the prognosis of patients receiving endovascular treatment. Therefore, we aimed to examine whether CTA-ER could predict favorable outcomes in patients undergoing endovascular treatment.
Methods:
We conducted a retrospective study enrolling patients with acute anterior circulation large-vessel occlusive stroke undergoing endovascular treatment between January 2016 and January 2023. All patients received noncontrast computed tomography and computed tomography angiography scans upon admission. Multivariate logistic regression analysis and receiver operator characteristic curve were used to assess the predictive efficacy in determining favorable outcomes. The favorable outcome at 90 days was a modified Rankin scale score of 0 to 2.
Results:
A total of 206 participants (median age, 68 [60-77] years; 77 women) were included in the study, with 82 (39.8%) individuals demonstrating favorable outcomes. Patients with favorable outcomes had lower noncontrast computed tomography net water uptake (6.42% versus 7.76%; P < 0.001) and CTA-ER (8.31% versus 10.56%; P < 0.001). Multivariate logistic regression analysis identified that CTA-ER was a significant predictor for favorable outcomes (P<0.05 in all models). Furthermore, the receiver operator characteristic analysis revealed that CTA-ER exhibited superior predictive performance, surpassing noncontrast computed tomography net water uptake (area under the curve, 0.707 versus 0.636, Delong test; P = 0.046).
Conclusion:
CTA-ER is a significant predictor of favorable outcomes in patients with acute large-vessel occlusion stroke undergoing endovascular treatment.
More Related Videos
09:32Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
06:11Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients
Published on: April 18, 2025
Related Concept Videos
01:10Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
01:19The Role of Ion Channels in Neuronal Computation
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
01:27Imaging Studies III: Computed Tomography
02:27Predicting Molecular Geometry
01:03Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
01:09Odds Ratio