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Single-Step Enrichment of a TAP-Tagged Histone Deacetylase of the Filamentous Fungus Aspergillus nidulans for Enzymatic Activity Assay
Published on: May 1, 2019
A new sesquiterpenoid from the Fungus Aspergillus sp. and its insecticidal activity
Ping Wu1, Yonghua Wu2, Yaming Chen2
1School of Engineering, Guangzhou College of Technology and Business, Guangzhou, 510880, China.
Abstract:
Chemical investigation of a mangrove-associated Aspergillus strain GXNU-31G, cultivated under saline fermentation conditions, yielded a new sesquiterpenoid named guxinusocapsa B (1) together with four congeners. Its planar framework and absolute stereochemistry were established through comprehensive analysis of 1D/2D NMR spectra, HR-ESI-MS data, and single-crystal X-ray crystallography. Bioassays of compounds 1-4 against the Asian citrus psyllid (Diaphorina citri) revealed that the newly characterized metabolite 1 elicited potent lethality, causing 95 % mortality at a dosage of 1000 mg kg-1.
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