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Updated: Jan 28, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[From vibration trauma to disturbed sensorimotor function: The beginning of a vicious circle in obstructive sleep
Ulrich Koehler1, Olaf Hildebrandt1, Mikail Aykut Degerli1
1Philipps-Universität Marburg, Pneumologie, Deutschland, Marburg.
Abstract:
Knowledge of the anatomy and neural innervation of the oropharynx and larynx is essential for understanding vital functions such as breathing, swallowing, coughing, and speaking. This article provides an overview of the sensorimotor innervation of the upper airway structures. The upper airway should be richly equipped with receptors and sensory nerve fibers due to its critical role in life-preserving protective reflexes. It is well established that patients with obstructive sleep apnea develop sensorimotor neuropathy over time. It is an interesting hypothesis that vibrations of the upper airway soft tissues and snoring are considered as likely trigger for this sensory neuropathy. Vibration and snoring could be the initial pathomechanism for a circulus vitiosus leading to obstructive sleep apnea.
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