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Drug Dosing: Geriatric Patients01:15

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Bioavailability refers to the extent and rate at which a drug reaches systemic circulation in its active form. Extent refers to the amount of the drug that makes it into circulation, while rate is the speed at which it enters circulation. It is influenced by several factors critical for optimizing drug formulations, dosing regimens, and therapeutic outcomes.Physicochemical properties of drugs and formulationsThe solubility, stability, and dissolution rate of a drug significantly impact its...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Influencing Factors and Participation in Ward Rounds for Geriatric Patients: A Descriptive Study Including Practical

Christina Wunner1,2, Noa-Charlotte Fischer2, Ann-Kathrin Weihrauch2

  • 1Department of Geriatrics, Klinikum Nürnberg, Paracelsus Private Medical University, Nuremberg, Germany.

Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society
|January 27, 2026
PubMed
Summary
This summary is machine-generated.

Optimizing geriatric patient participation in hospital ward rounds is crucial. While disruptions can be reduced, tools like pads and pens are underutilized by elderly patients.

Keywords:
geriatric ward roundhospitalizationpatient participationvisit

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Area of Science:

  • Geriatric Medicine
  • Hospital Administration
  • Patient Experience

Background:

  • Ward rounds are fundamental to inpatient care but lack specific guidance for older adults.
  • Enhancing geriatric patient involvement in ward rounds can improve care quality and satisfaction.

Purpose of the Study:

  • To detail geriatric ward round processes.
  • To evaluate patient satisfaction and identify opportunities to increase patient activity.
  • To quantify interruptions during ward rounds.

Main Methods:

  • Observational study over two months.
  • Data collected from 97 patients across 366 ward round visits.
  • Intervention: 58 patients provided with pads and pens for note-taking.

Main Results:

  • Average visit duration: 4 minutes 8 seconds.
  • 70.4% of visits were interrupted.
  • Physicians discussed an average of five topics; patients mentioned two.
  • Only 17.2% of patients used the provided pads and pens.

Conclusions:

  • Interruptions during geriatric ward rounds are frequent but potentially reducible.
  • Despite provision, patient use of note-taking tools (pads and pens) was low.