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Related Concept Videos

Clinical Trials01:16

Clinical Trials

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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Teeth01:15

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Shared Decision-Making for Periodontally Compromised Teeth: Study Protocol for an Ongoing Prospective Multicenter

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This study evaluated a structured shared decision-making (SDM) protocol for severe periodontitis patients. The SDM approach improved tooth preservation decisions and patient-centered outcomes compared to usual care.

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Area of Science:

  • Dental Medicine
  • Periodontology
  • Health Services Research

Background:

  • Treatment decisions for teeth with poor periodontal prognosis require balancing clinical evidence and patient values.
  • Shared decision-making (SDM) aligns clinical judgment with patient preferences but faces limited implementation in dental settings.
  • Structured SDM protocols are needed to manage severe periodontitis and hopeless-prognosis teeth.

Purpose of the Study:

  • To evaluate the effectiveness of a structured SDM protocol versus usual care for patients with severe periodontitis and hopeless-prognosis teeth.
  • To assess the impact of SDM on tooth preservation decisions, patient experience, and clinical outcomes.
  • To provide evidence for integrating structured SDM into dental practice for personalized care.

Main Methods:

  • A multicenter, before-and-after clinical trial across 12 dental centers in South Korea.
  • Intervention involved a three-step SDM protocol (team talk, option talk with decision aids, decision talk) for patients with stage III/IV periodontitis.
  • Data collected via Research Electronic Data Capture, with primary outcome as tooth preservation decisions.

Main Results:

  • The structured SDM protocol is expected to increase tooth preservation decisions compared to usual care.
  • Secondary outcomes will assess improvements in SDM measures, patient experience (satisfaction, regret), and treatment adherence.
  • Clinical outcomes, including periodontal condition and treatment costs, will also be evaluated.

Conclusions:

  • The study anticipates providing evidence supporting the integration of structured SDM protocols in dental practice.
  • Findings are expected to advance personalized and participatory approaches in managing severe periodontitis.
  • The research aims to improve patient-centered and clinical outcomes in periodontitis management.