Thrombotic Storm: A Challenging Case of Catastrophic Antiphospholipid Syndrome

We present the clinical case of a 68-year-old woman with a history of cerebrovascular disease, primary Sjögren's syndrome, and suspected antiphospholipid syndrome, admitted for acute diarrhea and fever. She showed good clinical and laboratory improvement under ciprofloxacin until the fifth day of hospitalization, when she developed abdominal pain with guarding, fever, and vomiting. Laboratory tests revealed elevated inflammatory markers and rhabdomyolysis. An abdominopelvic CT scan showed multiorgan ischemia, raising the suspicion of catastrophic antiphospholipid syndrome (CAPS).