Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

216
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
216
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

391
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
391
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

279
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
279
Centrifugation01:05

Centrifugation

7.8K
Centrifugation is a separation technique based on differences in density or size. It is commonly used to separate solids from aqueous interferents. During centrifugation, the sample is placed in centrifugation tubes and spun at high angular velocity, which allows centrifugal force to act differentially on the different densities or masses of the components. After spinning, the supernatant liquid is decanted. Depending on the specific application, either the pellet or the supernatant is retained...
7.8K
Emerging Adulthood01:27

Emerging Adulthood

656
Jeffrey Arnett's concept of emerging adulthood offers a framework to understand the unique developmental stage between adolescence and full-fledged adulthood, generally from ages 18 to 25. This period is marked by extensive exploration and shifts in identity, relationships, and career choices, a process known in psychology as role experimentation. Emerging adulthood reflects the evolving cultural expectations surrounding adulthood and the dynamic process of personal transformation during...
656
Sign Convention01:30

Sign Convention

3.5K
When analyzing a beam subjected to various loads, it is crucial to understand the internal forces and moments generated within the structure. These internal forces can be broadly classified into normal forces, shear forces, and bending moments. To determine these forces and moments, we use the method of sections and apply a specific sign convention based on their direction and the side of the section being analyzed.
The normal force acts perpendicular to the beam's cross-section and can...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Smartphone-Linked and Electricity-Free Platforms for Rapid Colorimetric Molecular Detection of Poultry Respiratory Viruses at the Point of Need.

Biosensors·2025
Same author

An integrated pH "Pen" for visual nucleic acid detection based on colorimetrical LAMP at point-of-care testing.

Analytical and bioanalytical chemistry·2025
Same author

Detection method for identifying duck hepatitis A virus 3 virulent and attenuated strains based on RPA CRISPR single-base recognition system.

Poultry science·2025
Same author

Digital recombinase polymerase amplification chip based on asymmetric contact angle composite interface.

Analytica chimica acta·2025
Same author

Chemical Heating for Minimally Instrumented Point-of-Care (POC) Molecular Diagnostics.

Biosensors·2024
Same author

Self-actuated microfluidic chiplet for two-stage multiplex nucleic acid amplification assay.

Lab on a chip·2024

Related Experiment Video

Updated: Jan 28, 2026

Microfluidic Applications for Disposable Diagnostics
10:21

Microfluidic Applications for Disposable Diagnostics

Published on: February 3, 2008

9.3K

Emerging Microfluidic Plasma Separation Technologies for Point-of-Care Diagnostics: Moving Beyond Conventional

Ergun Alperay Tarim1, Michael G Mauk1, Mohamed El-Tholoth2,3

  • 1Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Biosensors
|January 27, 2026
PubMed
Summary

Microfluidic devices offer a low-cost, rapid alternative to traditional centrifugation for plasma separation. These lab-on-a-chip systems enhance accessibility for point-of-care diagnostics and personalized medicine.

Keywords:
diagnosticlab-on-a-chip devicesmicrofluidicspersonalized medicineplasma separationpoint-of-care testing (POCT)

More Related Videos

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.0K
Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood
08:58

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

11.0K

Related Experiment Videos

Last Updated: Jan 28, 2026

Microfluidic Applications for Disposable Diagnostics
10:21

Microfluidic Applications for Disposable Diagnostics

Published on: February 3, 2008

9.3K
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.0K
Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood
08:58

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

11.0K

Area of Science:

  • Biomedical Engineering
  • Clinical Diagnostics
  • Microfluidics

Background:

  • Traditional centrifugation for plasma separation is costly and lab-dependent.
  • Limitations include expensive equipment, consumables, and trained personnel.
  • Need for accessible, rapid, and low-cost diagnostic methods is growing.

Purpose of the Study:

  • To review advances in microfluidic and lab-on-a-chip devices for plasma separation.
  • To categorize these systems by design, principles, and applications.
  • To discuss future directions for decentralized healthcare and personalized medicine.

Main Methods:

  • Review of current literature on microfluidic plasma separation.
  • Categorization based on design strategies and separation principles.
  • Analysis of application purposes and future trends.

Main Results:

  • Microfluidic systems enable rapid, low-cost plasma separation from small volumes.
  • These devices facilitate integration into portable, automated lab-on-a-chip platforms.
  • Emerging technologies support decentralization of healthcare and personalized medicine.

Conclusions:

  • Microfluidic plasma separation addresses limitations of traditional methods.
  • Lab-on-a-chip devices offer potential for point-of-care diagnostics.
  • Advances pave the way for broader accessibility and personalized healthcare solutions.