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The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): A Multi-Phase Program Overview.

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The Canadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT) network will improve supportive care for advanced cancer patients facing demoralization syndrome. It aims to build capacity, generate evidence, and inform policy for equitable access to psychedelic-assisted therapy (PAT).

Keywords:
cancerclinical trialsdemoralizationfear of death and dyingmindfulnesspatient-oriented researchpsilocybinpsychedelics

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Area of Science:

  • Oncology
  • Psychiatry
  • Health Services Research

Background:

  • Demoralization syndrome and psychosocial distress are significant challenges for Canadians with advanced cancer.
  • Existing supportive care models often fail to adequately address these complex needs.
  • Psychedelic-assisted therapy (PAT) shows promise for improving quality of life in palliative care settings.

Purpose of the Study:

  • To establish the Canadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT) to address gaps in supportive cancer care.
  • To develop a national network for research, training, and policy development in PAT for cancer patients.
  • To prepare Canada's oncology healthcare system for the potential implementation of PAT.

Main Methods:

  • CAN-PACT's strategy involves environmental scans, stakeholder engagement, and developing interdisciplinary networks.
  • The program includes developing training and education for clinicians, researchers, and patients.
  • A multi-center, randomized controlled trial of PAT for advanced cancer patients is planned, alongside feasibility pilot testing.

Main Results:

  • The network aims to set research priorities through structured stakeholder engagement.
  • CAN-PACT will pilot test intervention and assessment procedures for feasibility.
  • A multi-center randomized controlled trial will assess the efficacy of PAT for advanced cancer patients.

Conclusions:

  • CAN-PACT aims to enable equitable access to safe, evidence-based PAT for advanced cancer patients in Canada.
  • The network will build capacity and generate Canadian evidence to support PAT implementation.
  • Collaboration with policymakers is key to influencing healthcare policy on PAT in Canada.