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The Canadian Breast Cancer Symposium 2025: Meeting Report

Christine Brezden-Masley1, Katarzyna J Jerzak2, Nancy A Nixon3

  • 1Marvelle Koffler Breast Centre, Mount Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada.

Current Oncology (Toronto, Ont.)
|January 27, 2026
PubMed

Insights

The 2025 Canadian Breast Cancer Symposium highlighted advances in personalized breast cancer care, including new systemic therapies, radiation oncology de-escalation, and surgical techniques. Experts also addressed persistent gaps in diagnosis, access, and survivorship.

Area of Science:

  • Oncology
  • Medical Research

Background:

  • The Canadian Breast Cancer Symposium (CBCS) convenes experts to discuss breast cancer care advancements.
  • Personalized medicine is increasingly central to breast cancer treatment strategies.

Purpose of the Study:

  • To summarize key updates and discussions from the 2025 CBCS.
  • To identify emerging trends and persistent challenges in breast cancer management.

Main Methods:

  • The symposium featured presentations and discussions from patients, clinicians, and researchers.
  • Key areas covered included systemic therapy, radiation oncology, surgical oncology, and CNS metastases.

Main Results:

  • Significant progress was noted in systemic therapies, including CDK4/6 inhibitors, oral SERDs, PI3K/AKT-targeted agents, and antibody-drug conjugates.
  • Radiation oncology is moving towards de-escalation with ultra-hypofractionation and stereotactic approaches.
  • Surgical oncology focuses on reducing morbidity and lymphedema, while CNS metastasis management benefits from combined radiotherapy and systemic therapy.

Conclusions:

  • The 2025 CBCS showcased advancements in personalized breast cancer care, refining clinical practice.
  • Addressing gaps in diagnosis, access, and survivorship remains crucial for future research and improved patient outcomes.
Keywords:
CNS metastasesbreast cancernew advancespatient voicesurgical oncologysystemic therapy

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