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Updated: Jan 28, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
Published on: October 20, 2023
[Endovascular treatment for acute intestinal ischemia following superior mesenteric artery thrombosis]
A V Snitsar1, A V Kudrinskiy1,2,3, M A Sedgaryan2
1Moscow City Clinical Hospital No. 24, Moscow, Russia.
Abstract:
The study evaluated outcomes and risk factors of mortality in patients with acute arterial intestinal ischemia. A retrospective analysis enrolled 22 patients. Overall in-hospital mortality was 54.4%. Independent predictors of fatal outcomes were high WBC count (OR=1.188; p=0.005), elevated total bilirubin (OR=1.058; p=0.023), and high CCI (OR=1.272; p=0.037). Technical success of endovascular treatment reached 77.3%. High mortality rate is due to a combination of age, severity of comorbidities and pathophysiological characteristics of ischemic bowel injury. To further refine the treatment algorithm, it is advisable to establish multiple-center registries, implement interdisciplinary "intestinal teams" and further study risk factors for adverse outcomes.
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