[Evaluation of the effectiveness of perioperative nutritional metabolic support in surgical patients with burn disease]

To evaluate the efficacy, safety, and tolerability of nutritional metabolic support (NMS) in surgical patients with burn disease (BD) and to analyze its impact on the postoperative course.

All patients had severe burns with thermal burns covering up to 59% of the body surface area (trunk, chest, abdomen, back, and extremities in various combinations). These patients received conventional therapy appropriate to the stage of their illness (administration of analgesics, sedatives, antibiotics, infusion and transfusion therapy, correction of fluid-electrolyte, acid-base, and blood rheology balances, and surgical treatment of burn wounds). The study group consisted of 31 (61%) burn patients. Their comprehensive treatment included enteral nutritional support using specialized dietary therapeutic and preventive nutrition products - a Detoxifying Protein Cocktail twice daily (morning and lunchtime) and a Restorative Protein Cocktail once daily (evening), manufactured by LEOVIT nutrio - for 21 days. The control group included 20 burn patients who did not receive nutritional support. Burn severity was assessed using the Frank Burn Index (FBI), taking into account the area and depth of the lesion, as well as the presence of respiratory tract burns. Patients in the groups were comparable in severity. Treatment progress was monitored using general clinical laboratory testing methods.

The use of therapeutic metabolic enteral nutrition has a beneficial effect on the general condition of patients; Improves healing and epithelialization, accelerates burn scab rejection, improves clinical and biochemical blood parameters, intoxication and inflammation markers, enhances antioxidant defense, reduces inflammation, and improves patients' quality of life.

This study demonstrates the high clinical efficacy of domestically produced metabolic enteral nutrition products in surgical patients with burn disease. Effective domestic enteral nutrition ensures technological sovereignty and import substitution.