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Prosthetic Joint Infections in Trapeziometacarpal Arthroplasty: A Comprehensive Systematic Review
Guido Bocchino1,2, Silvia Pietramala1,2, Stella La Rocca1,2
1Department of Orthopedics, Ageing and Rheumatological Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.
Journal of Personalized Medicine
|January 27, 2026
Summary
Prosthetic infections after first trapeziometacarpal (TMC) joint replacement are rare (0.36%) but challenging to manage due to varied diagnostic and treatment approaches. Standardized protocols are needed for better outcomes in rhizarthrosis surgery.
Area of Science:
- Orthopedic Surgery
- Infectious Disease
- Biomaterials Science
Background:
- First trapeziometacarpal (TMC) joint osteoarthritis (rhizarthrosis) causes pain and functional loss, often requiring joint replacement.
- Prosthetic infections following TMC joint replacement are an understudied complication.
- Treatment choices for TMC joint replacement depend on individual patient factors.
Purpose of the Study:
- To systematically review the incidence, characteristics, and management of prosthetic infections after TMC joint replacement.
- To identify challenges and gaps in the current literature regarding TMC joint prosthetic infections.
Main Methods:
- Systematic review adhering to PRISMA guidelines (2000-2024).
- Searched Medline, Cochrane, and Google Scholar for randomized controlled trials and case series.
- Extracted and analyzed data on demographics, prosthesis types, infection rates, and management strategies.
Main Results:
- 15 infections (0.36%) reported across 63 studies involving 4165 TMC joint procedures.
- Staphylococcus aureus was identified in two cases.
- Management strategies varied widely, including antibiotics, debridement, and prosthesis removal with or without reimplantation.
Conclusions:
- Infections after TMC joint replacement are infrequent but pose significant management challenges due to inconsistent diagnostic criteria and treatment protocols.
- Standardized diagnostic and management protocols are crucial for improving patient outcomes.
- Further research, including multicenter trials, is needed to advance infection management in TMC joint prosthesis surgery.
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