Related Experiment Video
Updated: Jan 28, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Intraoperative Iatrogenic Aortic Dissection in Cardiovascular Surgery: Case Series and Literature Review
Jinjing Wu1, Tiantian Sun1, Peirong Lin1
1Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
Insights
Intraoperative iatrogenic aortic dissection (IAD) is a serious cardiac surgery complication. Prompt recognition and tailored strategies are crucial for managing IAD and improving patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Intraoperative iatrogenic aortic dissection (IAD) is a rare but severe complication of cardiac surgery.
- Limited evidence exists, with most reports based on small case series.
- This study provides insights from a high-volume center's experience.
Purpose of the Study:
- To summarize the experience with IAD at a high-volume cardiovascular center.
- To compare these findings with existing published data on IAD.
- To enhance understanding of IAD management and outcomes.
Main Methods:
- Retrospective review of 31 consecutive IAD cases from 2020 to 2024.
- Analysis of patient characteristics, operative details, and postoperative outcomes.
- Comparison with data from 17 published studies.
Main Results:
- IAD was identified intraoperatively in 90.3% of cases, predominantly involving the ascending aorta (80.6%).
- Common procedures included ascending aorta replacement (45.2%) and hemiarch replacement (22.6%).
- High rates of postoperative complications (low cardiac output, neurological injury, acute kidney injury) and an overall mortality of 38.7% were observed, compared to a pooled mortality of 32.8% in literature.
Conclusions:
- IAD presents a significant intraoperative challenge in cardiac surgery.
- Early detection and individualized surgical approaches are vital for effective management.
- Findings offer valuable insights for operative and perioperative decision-making in IAD cases.
Background:
Intraoperative iatrogenic aortic dissection (IAD) is an uncommon but serious complication of cardiac surgery, and available evidence remains limited, with most reports based on small series. This study summarizes our experience in a high-volume cardiovascular center and compares the findings with published data.
Methods:
We retrospectively reviewed 31 consecutive IAD cases treated at Anzhen Hospital from 2020 to 2024, assessing patient characteristics, operative details, and postoperative outcomes.
Results:
IAD was identified intraoperatively in 90.3% of patients, with ascending aortic involvement in 80.6%. The main procedures included ascending aorta replacement (45.2%) and hemiarch replacement (22.6%). Mean cardiopulmonary bypass time was 342.6 ± 133.8 min, and 38.7% required circulatory arrest. Major postoperative complications were low cardiac output syndrome (61.3%), neurological injury (25.8%), and acute kidney injury (45.2%). Overall mortality was 38.7%. Review of 17 original studies (1998-2025; >2000 patients) showed a pooled mortality of 32.8%. Patients in our cohort had higher operative risk and more complex procedures, which may partly explain the higher complication and mortality rates.
Conclusions:
IAD remains a major intraoperative challenge. Prompt recognition and individualized surgical strategies are essential. These findings provide further insight into intraoperative iatrogenic dissection and may help inform operative and perioperative decision-making.
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Resistors In Series
In a series circuit, the...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Series Resonance
Overview of the Cardiovascular System
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...

