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Area of Science:

  • Oncology
  • Health Economics
  • Pain Management

Background:

  • Cancer-related financial hardship, stemming from high out-of-pocket costs, is linked to poorer treatment outcomes.
  • The specific impact of financial hardship on clinical outcomes like pain intensity is not well understood.

Purpose of the Study:

  • To investigate the association between financial hardship and pain experienced by patients undergoing cancer treatment.
  • To examine the relationship between financial hardship and opioid utilization during cancer therapy.

Main Methods:

  • A retrospective cohort study analyzed data from 331 patients initiating systemic cancer therapy.
  • Financial hardship was assessed using the FACIT-COST instrument, while pain was monitored weekly via remote symptom monitoring.
  • Generalized linear models were employed to estimate the relative risks (RR) of pain and probabilities of opioid use associated with financial hardship.

Main Results:

  • Nearly half of the patients (48%) reported financial hardship.
  • Patients with financial hardship showed a 37% increased risk of moderate/severe pain over six months (RR, 1.37; 95% CI, 1.04 to 1.80).
  • Financial hardship correlated with higher probabilities of opioid use, irrespective of pain severity.

Conclusions:

  • Financial hardship is significantly associated with increased pain and greater opioid use in cancer patients.
  • Integrating financial screening into clinical practice is recommended to identify at-risk patients.
  • Interventions like financial navigation and tailored pain management may mitigate the adverse clinical effects of financial hardship.