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Updated: Jan 29, 2026

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Published on: March 25, 2011
Self-reported pain sensitivity in adults born extremely preterm compared to term-born controls: A matched cohort
Julie Vestavik Berge1, Silje Nesthus1, Merete Røineland Benestad2
1Department of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
Aim:
To compare self-reported pain sensitivity and the use of pain medication in young adults born extremely preterm (EP) with matched term-born controls.
Methods:
In this third follow-up of a population-based cohort study of individuals born EP (gestational age ≤28 weeks) in 1991-92, the Pain Sensitivity Questionnaire (PSQ) was administered together with health-related questions. Matched term-born controls served as a comparison group.
Results:
At 27 years of age, 24 (69%) EP-born and 26 (74%) term-born controls consented to participate. There were no significant differences between groups in PSQ total, moderate, or minor scores, nor in the use of pain medication. No associations were found between the number of painful procedures in the neonatal period and pain sensitivity at 27 years.
Conclusion:
Self-reported pain sensitivity and use of pain medication at 27 years of age did not differ between adults born extremely preterm and their term-born peers.
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