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Updated: Jan 29, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Radiotracers for imaging of schizophrenia
Mohsen Mohammadgholi1, Seyed Jalal Hosseinimehr2
1Food and Drug Deputy, Qazvin University of Medical Sciences, Qazvin, Iran.
Abstract:
Advanced imaging technologies, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET), have greatly improved our understanding of psychiatric disorders. These imaging modalities not only help us delve deeper into the neurobiology and underlying mechanisms of these disorders, but they also play a crucial role in enhancing clinical diagnosis, leading to better care for affected individuals. Research utilizing PET and SPECT has provided insights into the neurobiological underpinnings of schizophrenia, allowing for the visualization of brain activity and the assessment of neurotransmitter systems, particularly dopamine, which is often implicated in the pathophysiology of the disorder. Furthermore, radiotracers used in dopaminergic system imaging can help in comprehending how antipsychotic medications affect brain function and assist in evaluating treatment responses. Overall, PET and SPECT contribute valuable information to the understanding of schizophrenia, aiding both research and clinical settings.
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