Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

272
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
272
Psychodynamic Perspectives on Personality01:27

Psychodynamic Perspectives on Personality

1.6K
The psychodynamic perspective in psychology asserts that most personality functions operate unconsciously, outside of awareness. This means that the motives and emotions driving behavior often remain hidden, automatically buried in the unconscious mind as a defense mechanism to shield us from psychological distress. According to this theory, the unconscious mind contains thoughts, memories, and emotions that are too disturbing to face directly.
Psychodynamic theorists argue that unconscious...
1.6K
Cancer Prevention02:59

Cancer Prevention

8.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.1K
Social Cognitive Perspective on Personality01:30

Social Cognitive Perspective on Personality

1.0K
Social cognitive perspectives on personality emphasize the importance of conscious awareness, beliefs, expectations, and goals in shaping behavior. These perspectives incorporate behaviorist principles, such as learning through reinforcement and conditioning, but extend beyond them by highlighting human reasoning and planning. Unlike traditional behaviorist views, social cognitive theory focuses on how individuals reflect on their past experiences and plan for future outcomes by considering...
1.0K
Criticisms of the Evolutionary Perspective01:23

Criticisms of the Evolutionary Perspective

362
In a study where individuals posing as strangers offered compliments and proposed casual sex to students, the responses differed significantly based on gender. Not a single woman accepted the proposal, while 70% of the men agreed. This outcome provides a useful scenario to explore through the lens of evolutionary psychology and social learning theory, highlighting the diverse perspectives on human sexual behaviors.
Evolutionary psychology provides one explanation for these findings, suggesting...
362
The Behavioral Perspective on Personality01:19

The Behavioral Perspective on Personality

813
Behaviorists view personality as primarily shaped by environmental reinforcements and consequences. According to this perspective, behavior is influenced by external stimuli, and individuals adjust their actions based on rewards and punishments. Over time, learning histories — accumulated patterns of reinforcement — play a significant role in shaping personality. Behaviors that lead to positive outcomes are reinforced, while those resulting in negative outcomes are diminished.
813

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phosphate: Not Just a CKD Problem?

Kidney360·2026
Same author

Reply by Authors.

Urology practice·2025
Same author

Disproportionality Analysis of Urinary Stone Formation With Carbonic Anhydrase Inhibitors: A VigiBase Analysis.

Urology practice·2025
Same author

Limitations of ultrasound compared with computed tomography for kidney stone surveillance.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada·2025
Same author

Facility-Level Variation in Nephrology Care among Veterans after Urinary Stone Diagnosis.

Kidney360·2024
Same author

Urinary Response to Consuming Plant-Based Meat Alternatives in Persons with Normal Kidney Function: The SWAP-MEAT Pilot Trial.

Clinical journal of the American Society of Nephrology : CJASN·2024

Related Experiment Video

Updated: Jan 29, 2026

Perspectives on Neuroscience
26:41

Perspectives on Neuroscience

Published on: July 31, 2007

5.3K

Nephrolithiasis: A Paleolithic Perspective and Physiological Approach to Prevention.

Calyani Ganesan1, Lynda Frassetto2, Alan C Pao1,3,4

  • 1Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA;

Annual Review of Medicine
|January 27, 2026
PubMed
Summary
This summary is machine-generated.

The modern human diet, high in sodium and acid precursors, significantly increased the risk of nephrolithiasis (kidney stones) compared to the Paleolithic diet. Adopting ancient dietary patterns may reduce stone risk.

Keywords:
Paleolithicalkalidietnephrolithiasisthiazideurinary stone

More Related Videos

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.8K
PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP
06:36

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP

Published on: April 9, 2013

22.1K

Related Experiment Videos

Last Updated: Jan 29, 2026

Perspectives on Neuroscience
26:41

Perspectives on Neuroscience

Published on: July 31, 2007

5.3K
Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.8K
PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP
06:36

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP

Published on: April 9, 2013

22.1K

Area of Science:

  • Evolutionary Medicine
  • Nephrology
  • Nutritional Science

Background:

  • Nephrolithiasis (kidney stones) is a prevalent condition with complex etiologies.
  • The human diet has undergone drastic changes over evolutionary history, particularly in the last 10,000 years.

Purpose of the Study:

  • To explore the Paleolithic diet's influence on nephrolithiasis risk.
  • To investigate the impact of the agricultural and industrial food production revolutions on kidney stone formation.

Main Methods:

  • Review of evolutionary and historical dietary evidence.
  • Analysis of the shift from a high-potassium, low-sodium, alkali-rich Paleolithic diet to a modern diet.

Main Results:

  • The Paleolithic diet was characterized by high potassium, low sodium, and high alkali precursors.
  • Modern diets, influenced by agriculture and industrialization, are high in sodium and acid precursors, increasing stone risk.
  • The abrupt dietary shift challenged renal homeostasis, elevating stone formation risk.

Conclusions:

  • A return to Paleolithic-like dietary patterns may mitigate kidney stone risk.
  • While medications like thiazides, alkali, and empagliflozin show potential, further clinical trials are necessary to confirm their efficacy in preventing stone recurrence.