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Related Concept Videos

Drug Delivery: Overview01:16

Drug Delivery: Overview

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug Delivery: Enteral Route01:18

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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
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Drug Delivery: Miscellaneous Routes01:22

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
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Field Effect Transistor01:29

Field Effect Transistor

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Field-effect transistors (FETs) are integral to electronic circuits and distinguished by their three-terminal setup: the gate, drain, and source. These transistors operate as unipolar devices, which utilize either electrons or holes as charge carriers, in contrast to bipolar transistors, which use both types of carriers. The primary function of the FET is to modulate the flow of these carriers from the source to the drain through a channel. The voltage difference between the gate and source...
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Electric Field01:16

Electric Field

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Consider two point charges, each exerting Coulomb force on the other. It is possible to describe the Coulomb interaction via an intermediate step by defining a new physical quantity called the electric field.
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Generation of Alginate Microspheres for Biomedical Applications
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Microalgae as novel drug-delivery system for biomedical field.

Yueyou Dai1, Dandan Guo1,2, Aifang Li1,2

  • 1Medical College, Henan University of Chinese Medicine, Zhengzhou, People's Republic of China.

Drug Delivery
|January 27, 2026
PubMed
Summary

Microalgae show promise as drug delivery systems (DDS) due to their biocompatibility and targeted release capabilities. Research is advancing microalgae drug-delivery systems (MDDS) for improved medical treatments.

Keywords:
Microalgaedelivery systemdisease treatmentsafety evaluationtargeted therapeutic

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Area of Science:

  • Biomedicine and Drug Delivery
  • Biomaterials Science
  • Microalgal Biotechnology

Background:

  • Microalgae possess unique biological characteristics and diverse morphology, making them promising candidates for biomedical applications.
  • Their readily functionalizable surfaces enable efficient drug carrying and targeted release, addressing challenges like toxicity and immunogenicity.
  • Microalgae-based drug delivery systems (MDDS) are particularly relevant for treating diseases associated with hypoxia.

Purpose of the Study:

  • To comprehensively review the current research on microalgae drug-delivery systems (MDDS).
  • To explore strategies for enhancing drug loading capacity, stability, and targeting of microalgae-based DDS.
  • To discuss the future prospects and challenges of MDDS in clinical applications.

Main Methods:

  • Review of existing literature on microalgae applications in drug delivery.
  • Analysis of various microalgae-based strategies for drug encapsulation and release.
  • Examination of methods for improving the performance and tracking of MDDS.

Main Results:

  • Microalgae offer advantages over traditional biomaterials in drug delivery, including reduced toxicity and improved biocompatibility.
  • Current research focuses on optimizing microalgae for enhanced drug load, stability, and targeted delivery.
  • Strategies for target positioning and tracking of microalgae carriers are being developed.

Conclusions:

  • Microalgae hold significant potential for developing advanced drug delivery systems (DDS).
  • Further research and technological advancements in cultivation and production are crucial for expanding clinical applications of MDDS.
  • Microalgae-based DDS offer a promising avenue for more effective and safer therapeutic options.