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AI-Assisted Double-Headed Capsule Endoscopy: Multicentre Prospective Diagnostic Accuracy Study Across Small Bowel
Kamran Mushtaq1, Yun Jeong Lim2, Cristiano Spada3
1Southampton Interventional Endoscopy Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Diagnostics (Basel, Switzerland)
|January 28, 2026
Summary
AI-assisted double-headed capsule endoscopy significantly improves diagnostic accuracy and reduces reading time for small bowel evaluations. This technology offers superior specificity, supporting its use alongside expert review for enhanced patient care.
Area of Science:
- Gastroenterology
- Medical Imaging
- Artificial Intelligence
Background:
- Double-headed capsule endoscopy improves small bowel visualization but increases reading time.
- Evaluating diagnostic performance and efficiency of AI-assisted capsule endoscopy is crucial.
Purpose of the Study:
- To assess the diagnostic performance of AI-assisted double-headed capsule endoscopy (MiroCam MC2000).
- To compare the reading efficiency of AI-assisted versus standard manual reading modes for small bowel evaluations.
Main Methods:
- 242 patients underwent small bowel capsule endoscopy for various indications.
- Experienced readers reviewed videos in standard mode, followed by AI-assisted review (MiroCam AI Scan).
- Diagnostic findings were compared against a reference standard provided by two experts.
Main Results:
- AI-assisted reading demonstrated high sensitivity (95.3%) and superior specificity (96.5%) compared to standard reading.
- Reading time decreased by 52% with AI-assisted methods (18.26 min vs. 38.1 min).
- The positive findings rate was significantly higher with AI-assisted reading (83.6% vs. 80.2%, p=0.040).
Conclusions:
- AI-assisted reading provides high diagnostic accuracy and improved specificity for small bowel capsule endoscopy.
- This technology significantly reduces reading time, enhancing workflow efficiency.
- AI-assisted reading is a valuable adjunct to expert oversight in small bowel evaluations.
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