Related Experiment Video
Updated: Jan 29, 2026

13:08
Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass
Published on: August 10, 2017
11.4K
QSOX1: A Mysterious Golgi-Localized Disulfide Bond Catalyst and an Emerging Cancer Regulator
Shike Wang1, Guan-Yu Xiao2, Xiaochao Tan1
1Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Cancers
|January 28, 2026
Summary
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme linked to cancer progression. This review summarizes its role in cancer, highlighting mechanisms driving tumor growth and metastasis.
Area of Science:
- Biochemistry
- Molecular Biology
- Oncology
Background:
- Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme with disulfide isomerase and oxidoreductase activities.
- QSOX1 is crucial for protein folding, stability, and secretion.
- Increasing evidence links QSOX1 upregulation to various cancer types.
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