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Laser Deflection Acoustic Field Quantification: A Non-Invasive Measurement Technique for Focused Ultrasound Field

Yang Xu1,2, Hongde Liu3, Yaoan Ma3

  • 1Department of Biomedical Engineering, School of Life Science and Technology, and Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan 430074, China.

Bioengineering (Basel, Switzerland)
|January 28, 2026
PubMed
Summary
This summary is machine-generated.

A new non-invasive Laser Deflection Acoustic Field Quantification (LDAQ) method accurately measures high-pressure focused ultrasound fields. This technique enhances safety and efficacy for focused ultrasound therapies by providing reliable acoustic field characterization.

Keywords:
acoustic field reconstructionfocused ultrasoundlaser deflectionnon-invasive measurement

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Area of Science:

  • Acoustics
  • Biomedical Engineering
  • Optical Physics

Background:

  • Focused ultrasound (FU) is vital for clinical applications like tumor ablation and pain management.
  • Accurate acoustic field quantification is crucial for FU safety and efficacy.
  • Existing measurement methods have limitations, including invasiveness and inability to measure high sound pressures.

Purpose of the Study:

  • To develop and validate a non-invasive method for quantifying high-pressure focused ultrasound fields.
  • To address limitations of current acoustic measurement techniques.

Main Methods:

  • Proposed a non-invasive Laser Deflection Acoustic Field Quantification (LDAQ) method based on the laser deflection principle.
  • Constructed an experimental system using acousto-optic deflection, precision control, and synchronized triggering.
  • Employed tomographic scanning, Radon transforms for reconstruction, and adaptive weighted fusion to map optical signals to sound pressure.

Main Results:

  • The LDAQ technique successfully measured the acoustic field of an FU transducer.
  • Reconstructed results showed high consistency with hydrophone measurements and numerical simulations.
  • Achieved a root mean square error of 0.1102 (LDAQ vs. simulation) and 0.1422 (LDAQ vs. hydrophone).

Conclusions:

  • LDAQ enables non-invasive, high-precision quantification of megapascal-level focused acoustic fields.
  • This method offers a reliable approach for acoustic field characterization.
  • Supports optimization of FU treatments and standardization of FU devices.