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Updated: Jan 29, 2026
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Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
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Reproductive Longevity: Innovative Approaches Beyond Hormone Replacement Therapy.
Nida Jugulytė1, Daiva Bartkevičienė2
1Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
Medicina (Kaunas, Lithuania)
|January 28, 2026
Summary
Women
Area of Science:
- Biomedical science
- Women's health
- Reproductive endocrinology
Background:
- Increasing life expectancy highlights the importance of reproductive longevity.
- Menopause signifies the end of ovarian function and fertility.
- Hormone replacement therapy (HRT) is limited for menopausal symptom management.
Purpose of the Study:
- To review current and emerging strategies for reproductive aging.
- To discuss therapies for menopausal symptoms and fertility preservation.
- To explore novel ovarian regenerative approaches.
Main Methods:
- Narrative review of scientific literature.
- Analysis of hormonal and non-hormonal therapies.
- Examination of fertility preservation and ovarian regeneration techniques.
Main Results:
- Established therapies for menopausal symptoms exist.
- Fertility preservation techniques like oocyte vitrification are advancing.
- Emerging regenerative strategies show promise for ovarian aging.
Conclusions:
- Innovative solutions are needed for women's reproductive health and longevity.
- Personalized regenerative strategies may redefine reproductive aging.
- Future research should focus on delaying or reversing ovarian aging.
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